Dr. Melissa Grunlan
Department of Biomedical Engineering
Texas A&M University
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About Dr. Melissa Grunlan
Dr. Melissa Grunlan is the Charles H. and Bettye Barclay Professor of Biomedical Engineering at Texas A&M University (TAMU). She holds courtesy appointments in the Departments of Materials Science & Engineering and Chemistry.
After completing her B.S and M.S., Dr. Grunlan was employed at the H.B. Fuller Company (St. Paul, MN) for four years where she held titles of Chemist and then Senior Chemist. Next, she completed her Ph.D. at the University of Southern California. Following a post-doc in the Department of Chemistry (TAMU), Dr. Grunlan was hired as an Assistant Professor [2005]. She was awarded tenure at promoted to Associate Professor [2011], and then promoted to Full Professor [2017].
For the last 18 years, Dr. Grunlan has built an internationally-recognized research program focused on the development of polymeric biomaterials for medical devices as well as environmentally-friendly coatings. Her technologies include shape memory polymer bone scaffolds, synthetic cartilage, osteochondral implants, self-cleaning biosensor membranes, and antifouling silicones. Dr. Grunlan has received numerous awards from TAMU, including the prestigious Presidential Impact Fellow, and Chancellor EDGES Fellow. She is Fellow of the American Institute for Medical and Biological Engineering (AIMBE), the American Chemical Society (ACS), the ACS PMSE Division, and the Biomedical Engineering Society (BMES). She is a Senior Member of the National Academy of Inventors (NAI).
Dr. Grunlan served as Chair of the ACS Division of Polymeric Materials Science & Engineering. She was a standing member of the NIH Biotechnology and Surgical Sciences (BTSS) Study Section from 2019 – 2023. Dr. Grunlan is an Associate Editor of ACS Macro Letters. Her research has been reported in 104 peer-reviewed publications, and she holds 4 issued patents. Dr. Grunlan’s research has been sponsored by the NIH, NSF, DoD laboratories, and several companies.
Current Post-Doctoral Scholars
Current PhD Students
BMEN, Spring 2021 – present
Shape memory polymer scaffolds for orthopedic and gynecological applications
BMEN; Fall 2021 – present
Composite shape memory polymer scaffolds for bone defect repair
BMEN; Fall 2021 – present
Multinetork, electrostatic hydrogels for cartilage replacement
CHEM; Fall 2021 – present
Polyelectroylete hydrogel membranes for biosensors
CHEM; Fall 2021 – present
Shape memory scaffolds derived from silicon-based polymers
CHEM; Fall 2022 – present
Environmentally-benign anti-fouling marine coatings
Current Undergraduate Students
Thermoresponsive biosensor membranes
Undergraduate Research Scholar Thesis (2024): "Electrostatically Adhesive Double Network Membrane for Cargo-Carrying Adhesive Biosensor"
Undergraduate Research Scholars Thesis (2024): "Synthesis and Characterization of PLLA-PEG-PLLA Triblock Copolymers into PCL-Based SMP Bone Scaffolds"
Multi-network, adhesive hydrogels
Bioactive shape memory bone scaffolds
Multi-network, adhesive hydrogels
Electrospun shape memory polymer scaffolds
Shape memory polymer tissue scaffolds
Antifouling coatings for medical and marine applications
Self-cleaning biosensor membranes
Silicon-based polymers for regeneration and IOLs
Antifouling coatings for medical and marine applications
Former Post-Doctoral Scholars
Silicon-based scaffolds for bone regeneration
Silicones for 3D printing
Antifouling silicones for medical and marine applications
Former Ph.D. Students
Dissertation: "Multi-Network Hydrogels for Synthetic Cartilage Replacement". Currently: Senior Research Engineer - Solventum
Dissertation: "Amphiphilic Addiitives for Modification of Biomedical Silicones". Currently: Staff Process Engineer - J&J Vision
Dissertation: “Bioactive, Self-Fitting Scaffolds Prepared from Siloxane Based Shape Memory Polymers”. Currently: Principal R&D Scientist - Northrop Grumman
Dissertation: “‘Self-cleaning’ Hydrogel Membranes for Fully Implantable Glucose Biosensors”. Currently: Post-doc - Duke University
Dissertation: “Self-fitting Craniomaxillofacial (CMF) Bone Scaffolds with Tunable Properties. Currently: Assistant Professor, Dept. of Materials Science and Biomedical Engineering, U of Wisconsin - Eau Claire
Dissertation: Templated Hybrid Hydrogel Scaffolds for Osteochondral Repair. Currently: Product Manager - Abbott
Dissertation: “Thromboresistant Silicones and Polyurethanes Prepared with Amphiphilic Surface-Modifying Additives”. Currently: Materials Engineering Manager - VenoStent, Inc.
Dissertation: “Ultra-strong, Double Network Hydrogels for Implantable Glucose Biosensors and Synthetic Cartilage”. Currently: Bioengineer; 3D Systems Corp.
Dissertation: “Degradable PCL-PLLA Semi-IPN Network SMP Scaffolds for Cranial Bone Defect Repair”. Currently: Principal Scientist - Luna Labs USA
Antifouling coatings
Dissertation: “PEO-Silane Amphiphiles as Surface-Modifying Additives to Improve the Protein Resistance of Silicone”. Currently: Principal Materials Engineer - Medtronic.
Dissertation: “Self-Cleaning Membranes Based on Thermoresponsive Double Network Hydrogels”. Currently: Software Engineer - Google.
Dissertation: “Inorganic-Organic Hydrogel Scaffolds for Tissue Engineering Applications”. Currently: Global scientific communication leader - F. Hoffman-La Roche Ltd (Switzerland)
Dissertation: “Shape Memory Polymers with Si-Containing Segments”. Currently: Professor - University of Science & Technology (Beijing)
Dissertation: “Photocurable Inorganic-Organic Hydrogels for Biomedical Applications”. Currently: Senior Director of Life Sicence Division; Sunresin New Materials Co. Ltd.
Dissertation: “Enhancing Protein Resistance of PEO Modified Biomaterials”. Currently: Senior Vice President, Commericial & Digital Excellence; Azelis
Former M.S. Students
Thesis: “Biodegradable Si-Containing Elastomers for Tissue Engineering Scaffolds and Shape Memory Polymers
Former Undergraduate Students
Self-cleaning biosensor membranes
Bioactive shape memory bone scaffolds
Silicon-based bone scaffolds and intraocular lenses
Anti-fouling silicones
Anti-fouling silicones
Silicon-based bone scaffolds and intraocular lenses
Shape memory polymer scaffolds for bone repair
Amphiphilic silicones for intraocular lenses
Electrically conductive and antifouling silicones
Multi-network hydrogels for cartilage replacement
Composite shape memory scaffolds for bone repair
Undergraduate Research Scholars Thesis (2022): Polyampholyte Hydrogels for Implantable Glucose Biosensors
Shape memory polymer scaffolds for bone repair
Undergraduate Research Scholar Thesis (2022): “Lowering the Self-fitting Temperature of Shape Memory Polymer Scaffolds for Cranial Defect Repair"
Shape memory polymer scaffolds for bone repair
Multi-network hydrogels for cartilage replacement
Cartilage-mimetic hydrogels
Thromboresistant silicones
Undergraduate Research Scholar Thesis (2021): “Hydrogels with Regional Mechanical Properties”
Undergraduate Research Scholar Thesis (2021): “Stability Assessment of PEO-Silane Amphiphiles for Use in Intraocular Lenses”
Undergraduate Research Scholar Thesis (2018): “Assessment of Degradation for Porous PCL-PLLA Semi-IPN Shape Memory Polymer (SMP) Implants for Cranial Bone Defect Repair”
Hydrogel scaffolds for bone tissue regeneration
Shape memory polymer scaffolds for bone defect repair
Self-cleaning membranes for implanted glucose biosensors
Undergraduate Research Scholar Thesis (2020): “In vitro Real-time Degradation of ‘Self-fitting’ PCL-DA/PLA Semi-IPN Scaffolds for Cranial Bone Defects”
Undergraduate Research Scholar Thesis (2019): “The Effects of EtO Sterilization and Polydopamine on PCL-PLLA Scaffolds”
Undergraduate Research Scholar Thesis (2019): “Phosphonate Functionalized Inorganic-Organic Hybrid Hydrogels for Bone Regeneration”
Undergraduate Research Scholar Thesis (2019): “Impact of Polymer Architecture on PCL-DA/PLLA Semi-IPN Properties”
Undergraduate Research Scholar Thesis (2018): “Assessment of Degradation for Porous PCL-PLLA Semi-IPN Shape Memory Polymer (SMP) Implants for Cranial Bone Defect Repair”
Undergraduate Research Scholar Thesis (2019): “An Implantable Glucose Sensor Comprised of Fluorescence Assays a Self-Cleaning Hydrogel Membrane”
Hybrid hydrogels to treat osteochondral defects
Undergraduate Research Scholar Thesis (2019): “Development of Anti-fouling Materials for Blood-Contacting Devices”
Undergraduate Research Scholar Thesis (2018): “Incorporating Electrospun Fibers into Ultra-Strong Hydrogels”
Anti-clot and anti-infection coatings
Hydrogel membranes for biosensors and tissue replacement
Undergraduate Research Scholar Thesis (2016): “PCL Shape Memory Polymer Scaffolds Prepared with Variable Cross-link Density”
Hybrid hydrogel scaffolds for osteochondral repair
Self-fitting scaffolds for bone repair
Self-cleaning membranes for glucose biosensors
Hybrid hydrogel scaffolds for osteochondral repair
Undergraduate Research Scholar Thesis (2016): “Dynamic Whole Blood Study of Silicone Modified with PEO-Silane Amphiphiles”
Undergraduate Research Scholar Thesis (2016): “Macroporous PDMSstar-PEG-DA Hydrogels for Osteochondral Regeneration”
Undergraduate Research Scholar Thesis (2014): “PDMSstar-PEG Hydrogels for Osteochondral Tissue Engineering”
Shape memory polymer formas to treat bone defects
Shape memory polymers to treat bone defects, and hydrogel membranes
Thermoresponsive hydrogel membranes for biosensors
PEG-silane amphiphiles to improve clot resistance
Thermoresponsive hydrogel membranes for biosensors
Biodegradable shape memory polymers with Si-containing segments
Biodegradable shape memory polymers with Si-containing segments
Amphilic silicones with enhanced blood compatibility
Inorganic-organic hydrogel scaffolds for tissue engineering
PEG-silane amphiphiles to improve clot resistance
Amphilic silicones with enhanced blood compatibility
Undergraduate Research Scholar Thesis (2014): “Shape Memory Polymer (SMP) Foams for Bone Defect Repair”
PEG-silane amphiphiles to improve carbothane clot resistance
Amphilic silicones with enhanced blood compatibility
Thermoresponsive nanocomposite hydrogels
Shape memory polymers with Si-containing segments
Amphilic silicones with enhanced blood compatibility
PEG-silane amphiphiles to improve carbothane clot resistance
Thermoresponsive hydrogel membranes for biosensors
Inorganic-organic hydrogel scaffolds for tissue engineering
Inorganic-organic hydrogel scaffolds for tissue engineering
Thermoresponsive nanocomposite hydrogel membranes for glucose biosensors
Shape memory polymers for bone defect treatment
Thermoresponsive nanocomposite hydrogel membranes for glucose biosensors
Honors Fellow Thesis (2012): “Thermoresponsive Double Network Hydrogel Membranes for Glucose Biosensors”
Inorganic-organic hydrogel scaffolds for tissue engineering
Inorganic organic hydrogel scaffolds as gradients
Shape memory polymers with Si-containing segments
Shape memory polymers with Si-containing segments
Shape memory polymers with Si-containing segments
Biodegradable polymer scaffolds
Biodegradable polymer scaffolds
Preparation of antifouling surfaces with PDMS-block-PEO copolymers
Inorganic-organic hydrogels
Biodegradable polymer scaffolds
Shape memory polymers with Si-containing segments
Amphillic silicones
PDMS nanoparticles for biomaterial composites
Preparation of antifouling surfaces with PDMS-block-PEO copolymers
Inorganic-organic hydrogels
UV-curable PDMS/PEO polymers systems